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Creative Biolabs

IonON™ Human Kv7.2/Kv7.3 Recombinant Stable Cell Line

[CAT#: NCL-7P103]

Creative Biolabs provides numerous IonON cell models of ion channels to meet your drug discovery needs.

Species:
Human
Applications:
Ion Channel Assay
Cell Types:
Other Cells

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Product Overview

Description

Both potassium channels Kv7.2 and Kv7.3 function as voltage-gated delayed rectifiers. M currents are created in the brain by combining them. The potassium conductance known as M current, which slowly activates and deactivates, is crucial in controlling the excitability of neurons and their receptivity to synaptic input. Numerous central nervous system neurons also express this current. In anti-epileptic medication, M current enhancers are utilised, and blockers have been proven to improve memory and learning.

Cell Types

Other Cells

Applications

Ion Channel Assay

Application Notes

Electrophysiology assay (Conventional and automated patch clamp platforms)

Species

Human
Properties

Size

2 Vials of mycoplasma-free cells, 1 mL per vial aliquots containing 2M to 4M cells/mL in DMSO

Mycoplasma Testing

The cell line has been screened using the Mycoplasma Detection Kit to confirm the absence of Mycoplasma contamination.

Shipping

Dry ice.

Storage

Liquid Nitrogen

Research Use Only

For research use only

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Target Details

Target

Kv7.2/Kv7.3

Official Name

KCNQ2

Full Name

Kv7.2/Kv7.3

Alternative Names

KCNQ2; BFNC; BFNS1; EBN; EBN1; EIEE7; ENB1; HNSPC; KCNA11; KV7.2; KVEBN1; potassium voltage-gated channel subfamily Q member 2
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For Research Use Only. Not For Clinical Use.
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