Product
NeuroMab™ Anti-Collybistin BBB Shuttle Antibody, Clone L120/30
[CAT#: NRZP-0423-ZP83]
- Species Reactivity:
- Rat; Mouse
- Applications:
- WB; IHC; ICC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-VGAT BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 105-455 of rat Collybistin (also known as Rho guanine nucleotide exchange factor 9, Rac/Cdc42 guanine nucleotide exchange factor 9, PEM-2 homolog, ARHDH9, Arhgef9 and Kiaa0424, accession number Q9QX73)
Mouse: 99% identity (350/351 amino acids identical)
Human: 99% identity (348/351 amino acids identical)
>65% identity with Spata13 and ARHGEF4
Mouse: 99% identity (350/351 amino acids identical)
Human: 99% identity (348/351 amino acids identical)
>65% identity with Spata13 and ARHGEF4
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
L120/30
Applications
WB; IHC; ICC
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
VGAT
Official Name
VGAT
Full Name
Collybistin
Alternative Names
Vesicular GABA Transporter
Uniprot ID
Q9QX73
Product Pictures
IHC
Fig. 1 Adult rat cortex immunohistochemistry.
IHC
Fig. 2 Adult rat superior colliculus immunohistochemistry.
IHC
Fig. 3 Adult rat cerebellum immunohistochemistry.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
