NeuroMab™ Anti-LILRB2 Antibody(NRP-0422-P554)

Product Overview

Description

The anti-LILRB antibody interacts with one or more members of the LILRB receptor family, useful for modulating inflammatory macrophage activation, lymphocyte activation, and phagocytosis.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Applications

ELISA; FC; IHC; In Vitro; In Vivo

Relevant Diseases

Alzheimer's Disease

Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

>95% by SDS PAGE or HPLC

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only

Target

LILRB2

Official Name

LILRB2

Full Name

LILRB

Alternative Names

LILRB2; ILT4; MIR10; LIR2; MIR-10; LIR-2; leukocyte immunoglobulin like receptor B2; ILT-4; CD85D

Product Pictures

FCM

Figure 1 shows T cell proliferation in a mixed lymphocyte reaction (MLR) setting.

Both C320-168 and C320-179 bind to the longer (72-251) and shorter (84-251) isoforms of soluble split TL1a.

FuncS

Figure 2 shows the production of IFNγ by exemplary anti-LILRB 2 antibodies 13h1.g2 and 6g6.h7 and the pan-anti-LILRB 1/2/3 antibody 9c9.e 6 in a two-way mixed lymphocyte reaction (MLR) setting.

Both C320-168 and C320-179 bind to the longer (72-251) and shorter (84-251) isoforms of soluble split TL1a.

ELISA

Figure 3 shows the ELISA binding of anti-LILRB antibodies to the full-length extracellular LILRB2 proteins Lilrb2_01, Lilrb2_02, Lilrb2_03 and Lilrb2_04.

Both C320-168 and C320-179 bind to the longer (72-251) and shorter (84-251) isoforms of soluble split TL1a.