NeuroMab™ Anti-Nav1.7 BBB Shuttle Antibody(NRZP-1022-ZP2488)
[CAT#: NRZP-1022-ZP2488]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA; Block; Inhib; In Vitro
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Applications
ELISA; Block; Inhib; In Vitro
Relevant Diseases
Pain; Epilepsy
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
SCN9A
Official Name
SCN9A
Full Name
sodium voltage-gated channel alpha subunit 9
Alternative Names
SCN9A; ETHA; FEB3B; GEFSP7; HSAN2D; NE-NA; NENA; Nav1.7; PN1; SFNP; sodium voltage-gated channel alpha subunit 9
Product Pictures
FuncS
Fig.1 shows the functional effects of certain monoclonal antibodies on human Nav1.7 current in HEK cells.
1080 monoclonal antibody produces a ˜26% inhibition of Nav1.7 currents at 25 μg/ml.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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