Product
NeuroMab™ Anti-Parvalbumin BBB Shuttle Antibody, Clone L114/3
[CAT#: NRZP-0423-ZP338]
- Species Reactivity:
- Rat; Mouse
- Applications:
- WB; IHC; ICC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-Parvalbumin BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 1-110 (full-length) of rat Parvalbumin (also known as Parvalbumin alpha, Pvalb and Pva, accession number P02625)
Mouse: 95% identity (104/110 amino acids identical)
Human: 92% identity (101/110 amino acids identical)
~50% identity with Oncomodulin
Mouse: 95% identity (104/110 amino acids identical)
Human: 92% identity (101/110 amino acids identical)
~50% identity with Oncomodulin
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
L114/3
Applications
WB; IHC; ICC
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
Parvalbumin
Official Name
PVALB
Full Name
Parvalbumin
Alternative Names
Parvalbumin Alpha
Uniprot ID
P02625
Product Pictures
IHC
Fig. 1 Adult rat hippocampus striatum immunohistochemistry.
IHC
Fig. 2 Adult rat thalamus immunohistochemistry.
IHC
Fig. 3 Adult rat hippocampus immunohistochemistry.
IB
Fig. 4 Adult rat brain low-speed pellet immunoblot.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
