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Creative Biolabs

NeuroMab™ Mouse Anti-Alpha I spectrin Monoclonal Antibody (CBP2192)

[CAT#: NAB201054LS]

Anti-Alpha I spectrin Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat
Applications:
WB; ICC

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Product Overview

Description

Spectrin is an intracellular cytoskeletal protein that provides structure to eukaryotic cells and helps maintain plasma membrane integrity. Alpha-1 Spectrin, encoded by the SPTA1 gene, is found primarily in erythrocytes and in the cerebellum

Immunogen

Recombinant α spectrin SH3 domain

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2192

Applications

WB; ICC

Application Notes

WB (1.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation

Conjugation

Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1625
Product Properties

Form

Liquid

Formulation

PBS (no preservatives or carrier proteins).

Concentration

1.0 mg/ml

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Endotoxin Level

Low Endotoxin

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

Alpha I spectrin

Official Name

SPTA1

Full Name

Spectrin, alpha 1

Alternative Names

SPTA1; EL2; HPP; HS3; SPH3; SPTA; Spectrin; alpha 1; spectrin alpha; erythrocytic 1

Gene ID

6708 (Human); 20739 (Mouse)

Uniprot ID

P20549 (Human); P08032 (Mouse)
References

1. De Matteis MA, Morrow JS. 2000. J. Cell Sci. 113:2331-43.
2. Bennett V, Gilligan DM. 1993. Annu. Rev. Cell Biol. 9:27-66.
Publications

Publications (0)

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