NeuroMab™ Mouse Anti-Mucin 2 Monoclonal Antibody (CBP2589)

Product Overview

Description

Mouse anti-human mucin 2 antibody, recognizes human mucin 2 (MUC-2), and does not cross-react with MUC-1, MUC-3 or MUC-4. In formalin-fixed, paraffin-embedded tissue sections, mouse anti-human mucin 2 antibody recognizes malignant colonic mucosa as well as normal mucosa. Epitope mapping indicates that the mouse anti-human Mucin 2 antibody recognizes the sequence PTGTQ within the region of the Mucin 2 tandem repeat (Uray et al., 1999).

Immunogen

MUC-2 tandem repeat peptide.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2589

Applications

Application Notes

FC: 1/10

Relevant Diseases

Alzheimer's Disease; Neurodegenerative Disease

Research Areas

Neuroregeneration

Conjugation

Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1883

Product Properties

Form

Liquid

Formulation

PBS, 0.09% Sodium Azide, 1% BSA

Preservatives

YES

Concentration

0.05 mg/ml

Purification

Protein G

Endotoxin Level

Low Endotoxin

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend micr°Centrifugation before use.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

MUC2

Official Name

MUC2

Full Name

Mucin 2, Oligomeric Mucus/Gel-Forming

Alternative Names

Mucin 2, Oligomeric Mucus/Gel-Forming; Mucin 2, Intestinal/Tracheal; MUC-2; SMUC; Intestinal Mucin-2; Mucin-2; MLP;

Gene ID

4583(Human); 17831(Mouse); 24572(Rat)

Uniprot ID

Q02817(Human); Q80Z19(Mouse); Q62635(Rat)

References

1. Filipe, M.I. et al. (1996) Expression of a peptide epitope of the colonic mucin MUC2 in precursor lesions to gastric carcinoma.
2. Paulsen, F.P. et al. (2003) Characterization of mucins in human lacrimal sac and nasolacrimal duct.
3. Price, M.R. et al. (1999) Separation of distinct MUC2 mucin glycoforms using two anti-peptide monoclonal antibodies.
4. Price, M.R. et al. (1993) Immune recognition of human colonic-tumour-associated MUC-2 mucins using an anti-peptide antibody.
5. Tugyi, R. et al. (2005) Partial D-amino acid substitution: Improved enzymatic stability and preserved Ab recognition of a MUC2 epitope peptide.

Publications