Human CHO-K1/ADRA1D Stable Cell Line

[CAT#: NCL20120019CR]

ADRA1D Adrenoceptors Stable Cell Line

Species:: Human

Applications:: GPCR Screening

Cell Types:: Other Cells

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Request Pricing

Inquiry

Product Overview

Description

Α1-ARs belong to the G protein-coupled receptor family and consist of single polypeptide chains that are predicted to form seven transmembrane spanning domains. With similar pharmacological and signaling properties, α1-AR subtypes act through Gq/11 proteins to activate phospholipase C, increase inositol 1,4,5-trisphosphate production, and increase intracellular Ca2+. ADRA1B functions in diverse settings include vasoconstriction and myocardial contractility, neuronal dopaminergic responses, dendritic cell migration and inflammatory responses, as well as neuroendocrine regulation of fertility.

Cell Types

Other Cells

Applications

GPCR Screening

Research Areas

GPCR; Neural Signal Transduction

Species

Human

Properties

Size

>1x10^6 Cells

Form

Frozen cells

Culture Medium

Ham's F12, 10% FBS, 400 μg/ml G418

Freeze Medium

45% culture medium, 45% FBS, 10% DMSO

Receptor

ADRA1D

Family

Adrenoceptors

Strain

ADRA1D Cell Line

Cell Purity

>95%

Shipping

Dry ice

Storage

Liquid nitrogen immediately upon delivery

Handling Advice

Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Warnings

Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents.

Target Details

Target

ADRA1D

Official Name

ADRA1D

Full Name

Alpha 1D adrenoceptor

Alternative Names

Alpha 1D adrenoceptor; RA42; adrenergic receptor delta1; adrenergic receptor; alpha 1d; adrenergic receptor; delta1; alpha 1D-adrenoceptor; alpha-1D adrenergic receptor; Gpcr8; Adra-1; alpha1D-AR

Gene ID

148(Human); 11548(Mouse); 24173(Rat)

Uniprot ID

P35368(Human); P97718(Mouse); P23944(Rat)

References

1. Zhang, W., Chen, L., Ma, Z., Du, L., & Li, M. (2014). Design, synthesis and biological evaluation of naphthalimidebased fluorescent probes for α1-adrenergic receptors. Drug Discoveries & Therapeutics, 8(1), 11-17.

Publications