Product
Human HEK293/MCH1 Stable Cell Line
[CAT#: NCL20120082CR]
Melanin-concentrating Hormone Receptor 1 Stable Cell Line
- Species:
- Human
- Applications:
- GPCR Screening
- Cell Types:
- HEK293; GPCR Cell
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Overview
Description
It is an integral plasma membrane protein that binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Melanin-concentrating hormone (MCH) is an important neuropeptide hormone involved in multiple physiological processes. Peptide derivatives of MCH have been developed as tools to aid researches that involve potent radioligands, receptor selective agonists, and potent antagonists. These tools have been used to further understand the role of MCH's physiology primarily in rodents.
Cell Types
HEK293; GPCR Cell
Applications
GPCR Screening
Research Areas
GPCR; Neural Cell
Species
Human
Properties
Size
>1x10^6 Cells
Form
Frozen cells
Culture Medium
DMEM, 10% FBS, 200 μg/ml Zeocin
Freeze Medium
45% culture medium, 45% FBS, 10% DMSO
Receptor
MCH1/GPR24
Family
Melanin concentrating hormone receptor
Strain
MCH1 Cell Line
Cell Purity
>95%
Shipping
Dry ice
Storage
Liquid nitrogen immediately upon delivery
Handling Advice
Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.
repeated exposure.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Warnings
Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents.
Target Details
Target
MCH1
Official Name
MCH1
Alternative Names
MCH1 receptor; SLC1; MCHR1; MCH-1R; gpr 24; SLC-1; GPR24; MCH1R; G protein-coupled receptor 24; MCH receptor 1; MCH-R1; MCHR; MCHR-1; melanin-concentrating hormone receptor 1; somatostatin receptor-like protein; Gpr24-9; AW049955
References
1. Ghosh, E., Dwivedi, H., Baidya, M., Srivastava, A., Kumari, P., Stepniewski, T.,.. & Roy, D. (2019). Conformational sensors and domain swapping reveal structural and functional differences between β-arrestin isoforms. Cell reports, 28(13), 3287-3299. 2. Hernandez-Gordillo, V., & Chmielewski, J. (2014). Mimicking the extracellular matrix with functionalized, metal-assembled collagen peptide scaffolds. Biomaterials, 35(26), 7363-7373.
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
