iNeu™ GABANeurons
GABANeurons differentiated from Human iPS cells, frozen
- Species:
- Human
- Cell Types:
- GABANeuron
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Description
iNeu GABANeurons is a mixed group of Human cerebral cortical neurons derived from iPS cells, with natural electrical and biochemical activities. They overcome the limitations of existing models.
Features
Rapid formation of neural networks and functional synapses
Expression of relevant neurological therapeutic targets and pathways
Long-term viability and demonstrated reproducibility
Reliable supply in cryopreserved format
Cell Types
Application Notes
Functional tau and β-amyloid toxicity pathways, long-term viability, and flexible product format enable high-throughput screening for novel drug candidates
Autism disease research
Demonstrated prefrontal cortex ionotropic glutamate receptors, GABAA receptor, and synaptic functionality drive interrogation of neurological diseases, such as autism
Infectious disease studies
Susceptibility to variNeua zoster virus infection and ability to maintain viral latency and reactivation
Therapeutic potency testing
High sensitivity, dose-response, and biological responses to Clostridium botulinum neurotoxin (BoNT) aid replacement of the gold-standard mouse bioassay for BoNT potency testing
Neurotoxicity assessment
Compatibility with a wide range of high-content, high-throughput platforms enables assessment of pharmaceutical and environmental neurotoxicity
Species
Size
Tissue Source
Age
Mycoplasma Testing
Shipping
Storage
Research Use Only
Quality Control
Gender
Donor Health
Ethnicity
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