iNeu™ Human Neural Stem Cells - Spinocerebellar Ataxia Type 2 (SCA2) Patient, Donor 57
[CAT#: NRZP-0622-ZP84]
Q&As(4)
Human iPSC-derived neural stem cells from patients with spinocerebellar ataxia type 2 (SCA2)
- Species:
- Human
- Applications:
- Cell Culture
- Cell Types:
- Neural Stem Cells
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Product Overview
Description
Spinocerebellar ataxia is a rare inherited autosomal dominant disorder that causes progressive cerebellar ataxia. There are different subtypes of the disease, which are based on mutations in the Ataxin gene family as well as in the calcium channel subunit genes. Creative Biolabs cell lines derived from spinocerebellar ataxia patients as well as familial and unaffected controls are excellent models for studying this rare genetic disorder. Creative Biolabs now offers custom human iPSC-derived brain cells or cardiomyocytes derived from patients with spinocerebellar ataxia.
Cell Types
Neural Stem Cells
Applications
Cell Culture
Relevant Diseases
Ataxia
Species
Human
Properties
Tissue Source
Fibroblasts
Shipping
Dry ice
Storage
Liquid Nitrogen Vapor Phase
Research Use Only
For research use only. They are not approved for human or animal use, or for application in in vitro diagnostic procedures.
Donor Information
Gender
Male
Donor Age
58
Donor Health
Disease
Additional Donor Information
Gene Type: ATXN2
Publications
Publications (0)
Neural Cell Lines
Customer Reviews and Q&As
Q&As
What reagents are used for thawing, maintaining neuronal stem cells in culture and for their differentiation into terminal neurons?
We have three standard neuronal protocols for NSCs: Enriched Cortical Neuron protocol, Striatal Neuron protocol and Spontaneous Differentiation protocol. If you give us guidance of which, we would be happy to provide you with further advice.
What genetic stability tests were performed on the NSCs?
Our iPSCs go through extensive QC tests. The testing includes sterility, Sendai clearance (where relevance), viability, karyotyping, confirmation of genetic mutation and phenotyping against a range of pluripotency markers including SSEA-1, SSEA-3, SSEA-4, NANOG, OCT3/4 and TRA-1-60.
What pluripotency tests were performed on the NSCs?
We have confirmed the pluripotency of our iPSCs by differentiating them into a wide-range of different cell types such as NSCs, cortical neurons, astrocytes, microglia, monocytes, macrophages, interneurons, dopaminergic, striatal, sensory neurons, motor neurons and atrial & ventricular cardiomyocytes.
Do you have NSCs obtained from healthy donors?
Yes.
iNeu™ Human Neural Stem Cells (Male), Source Fibroblasts (74 Yr Donor), Cat.#NCL-2101-ZP04
iNeu™ Human Neural Stem Cells (Female), Source Fibroblasts (64 Yr Donor), Cat.#NCL-2101-ZP05
For Research Use Only. Not For Clinical Use.
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