NeuroMab™ Anti-CD3 BBB Shuttle Antibody(NRZP-1022-ZP3912)
[CAT#: NRZP-1022-ZP3912]
- Host Species:
- Human
- Species Reactivity:
- Human
- Applications:
- FC; In Vitro; In Vivo
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Human
Applications
FC; In Vitro; In Vivo
Relevant Diseases
Alzheimer's Disease
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
CD3
Official Name
CD3
Full Name
CD3e molecule, epsilon (CD3-TCR complex)
Alternative Names
CD3; CD3e molecule; epsilon (CD3-TCR complex)
Product Pictures
FCM
Figure 1 Binding of antibodies containing MF5196 VH; MF5603 VH; MF5616 VH; MF5626 VH; MF5630 VH; chain.
FCM
Figure 2 Binding of the PG form to membrane-expressed CD3 on HPB-ALL cells All of these examples bound to CD3.
FCM
Figure 3 Binding of the PG form to membrane-expressed CD3 on HPB-ALL cells All of these examples bound to CD3.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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