NeuroMab™ Anti-EPHA2 BBB Shuttle Antibody(NRZP-1022-ZP3860)
[CAT#: NRZP-1022-ZP3860]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- In Vitro; In Vivo
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Applications
In Vitro; In Vivo
Relevant Diseases
Glioblastoma Multiforme
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
EPHA2
Official Name
EPHA2
Full Name
EPH receptor A2 (ephrin type-A receptor 2)
Alternative Names
EPHA2; Epha2; AW545284; Eck; Myk2; Sek-2; Sek2; ARCC2; CTPA; CTPP1; CTRCT6; EPH receptor A2; ECK
Product Pictures
FCM
Figure 1 shows the results of A549 tumor xenografts treated subcutaneously with SPL1 and their slow regrowth after cessation of administration.
Publications
Publications (0)
Kits
Neural Antibodies
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
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