NeuroMab™ Anti-PSD-93/Chapsyn-110 scaffold protein BBB Shuttle Antibody, Clone N18/28
[CAT#: NRZP-0423-ZP354]
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB; IHC; ICC
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-PSD 93 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 1-852 (full-length) of rat Chapsyn-110 (also known as Channelassociated protein of synapse-110, Postsynaptic density protein PSD-93, Disks large homolog 2, Dlg2 and Dlgh2, accession number Q63622)
Mouse: 99% identity (846/852 amino acids identical)
Human: 94% identity (826/870 amino acids identical)
>60% identity with other MAGUK family members (SAP97/Dlg1, SAP102/Dlg3 and PSD-95/Dlg4)
Mouse: 99% identity (846/852 amino acids identical)
Human: 94% identity (826/870 amino acids identical)
>60% identity with other MAGUK family members (SAP97/Dlg1, SAP102/Dlg3 and PSD-95/Dlg4)
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
N18/28
Applications
WB; IHC; ICC
Application Notes
Does not cross-react with SAP97, SAP102 or PSD-95
Research Areas
Scaffolds
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
PSD 93
Official Name
DLG2
Full Name
PSD-93/Chapsyn-110
Alternative Names
DLG2; PPP1R58; PSD-93; PSD93; chapsyn-110; discs large homolog 2; discs large MAGUK scaffold protein 2
Uniprot ID
Q63622
Publications
Publications (0)
Neural Antibodies
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
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