Product
NeuroMab™ Anti-VGAT BBB Shuttle Antibody, Clone L118/80
[CAT#: NRZP-0423-ZP461]
- Species Reactivity:
- Rat; Mouse
- Applications:
- WB; IHC; ICC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-SLC32A1 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 1-133 (cytoplasmic N-terminus) of mouse VGAT (also known as GABA and glycine transporter, Vesicular inhibitory amino acid transporter, Vesicular GABA transporter, Solute carrier family 32 member 1, VIAAT and SLC32A1, accession number O35633)
Rat: 99% identity (132/133 amino acids identical)
Human: 96% identity (128/134 amino acids identical)
Rat: 99% identity (132/133 amino acids identical)
Human: 96% identity (128/134 amino acids identical)
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
L118/80
Applications
WB; IHC; ICC
Research Areas
Transporters
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
SLC32A1
Official Name
SLC32A1
Full Name
VGAT
Alternative Names
SLC32A1; VGAT; VIAAT; solute carrier family 32 member 1
Uniprot ID
O35633
Product Pictures
IHC
Fig. 1 Adult rat brain striatum and globus pallidus immunohistochemistry.
IHC
Fig. 2 Adult rat hippocampus immunohistochemistry.
IHC
Fig. 3 Adult rat superior colliculus immunohistochemistry.
IB
Fig. 4 Adult rat brain membrane immunoblot.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
