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Creative Biolabs

Mouse Anti-Tyrosine Hydroxylase Monoclonal Antibody (CBP2207)

[CAT#: NAB201077LS]

Anti-Tyrosine Hydroxylase Monoclonal Antibody [Alexa Fluor 488]

Host Species:
Mouse
Species Reactivity:
Human; Rat; Mouse
Applications:
IHC-P

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Product Overview

Description

Tyrosine hydroxylase, also known as tyrosine 3-monooxygenase, is the enzyme that converts amino acid L-Tyrosine to L-3, 4-Dihydroxyphenylalanine (L-DOPA). L-DOPA is a precursor to dopamine, which is then converted to norepinephrine and epinephrine (adrenaline). Dopamine, norepinephrine and epinephrine are all important neurotransmitters. Alterations in the activity of tyrosine hydroxylase may be involved in a number of neurological diseases such as Parkinson's and schizophrenia.

Immunogen

This monoclonal antibody was raised against purified Tyrosine Hydroxylase from rat Pheochromocytoma tumor.

Species Reactivity

Human; Rat; Mouse

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a, κ

Clone Number

CBP2207

Applications

IHC-P

Application Notes

IHC-P (0.2-1.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation

Conjugation

Alexa Fluor 488
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Handling Advice

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

Tyrosine Hydroxylase

Official Name

TH

Full Name

Tyrosine hydroxylase

Alternative Names

TH; Th; DYT14; DYT5b; TYH; tyrosine hydroxylase; Tyrosine hydroxylase

Gene ID

7054(Human); 21823(Mouse); 25085(Rat)

Uniprot ID

P07101(Human); P24529(Mouse); P04177(Rat)
Publications

Publications (0)

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