NeuroMab™ Mouse Anti-CD11b/CD11c Monoclonal Antibody (CBP2218)
[CAT#: NAB2010105LS]
Anti-CD11b/CD11c Monoclonal Antibody [Alexa Fluor 488]
- Host Species:
- Mouse
- Species Reactivity:
- Human; African green monkey; Baboon; Chimpanzee; Cynomolgus; Rhesus; Squirrel Monkey
- Applications:
- FC
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
inquiryProduct Overview
Description
CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αX and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.
Species Reactivity
Human; African green monkey; Baboon; Chimpanzee; Cynomolgus; Rhesus; Squirrel Monkey
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1, κ
Clone Number
CBP2218
Applications
FC
Application Notes
FCM (5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation
Conjugation
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1644
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.
Concentration
Batch Dependent
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Endotoxin Level
Low Endotoxin
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Handling Advice
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
ITGAM; ITGAX
Official Name
ITGAM; ITGAX
Full Name
Integrin alpha M/Integrin, alpha X
Alternative Names
ITGAM; CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6; integrin subunit alpha M; ITGAX; CD11C; SLEB6; integrin subunit alpha X
References
1. Petty H. 1996. Immunol. Today 17:209.
2. Springer T. 1994. Cell 76:301.
3. Ihanus E, et al. 2007. Blood 109:802-810.
2. Springer T. 1994. Cell 76:301.
3. Ihanus E, et al. 2007. Blood 109:802-810.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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