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Creative Biolabs
Product

Mouse Anti-Rat CD11b/c Monoclonal Antibody (CBP3862)

[CAT#: NAB2012400LS]

Anti-CD11b/c Monoclonal Antibody [Alexa Fluor 488 ]

Host Species:
Mouse
Species Reactivity:
Rat
Applications:
FC; IHC

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Product Overview

Description

CD11c is a 150 kD glycoprotein, also known as αX integrin, CR4 and p150. CD11c and β2 integrin (CD18) form an αXβ2 heterodimer. It is mainly expressed on dendritic cells, NK cells, a part of intestinal intraepithelial lymphocytes (IEL) and some activated T cells. αXβ2 integrin plays an important role in cell-cell contact by binding to its ligand iC3b, fibrinogen and CD54.

Immunogen

Rat peritoneal macrophages.

Species Reactivity

Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a, κ

Clone Number

CBP3862

Applications

FC; IHC

Application Notes

FCM (≤0.25 µg per 106 cells in 100 µL volume); IHC (2.5-10.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Alexa Fluor 594; Alexa Fluor 488; Alexa Fluor 498; Alexa Fluor 647; Alexa Fluor 700; APC; APC/Cyanine 7; APC/Fire 750; Biotin; Brilliant Violet 421; Brilliant Violet 510; Brilliant Violet 570; Brilliant Violet 570; Brilliant Violet 605; Brilliant Violet 650; Brilliant Violet 711; Brilliant Violet 750; Brilliant Violet 785; FITC; HRP; PE; Pacific Blue; PE/Cyanine 5; PE/Cyanine 7; PerCP; Spark YG 570
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

ITGAM; ITGAX

Official Name

ITGAM; ITGAX

Full Name

Integrin alpha M/Integrin, alpha X

Alternative Names

ITGAM; CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6; integrin subunit alpha M; ITGAX; CD11C; SLEB6; integrin subunit alpha X

Gene ID

3684 (Human); 16409 (Mouse); 25021 (Rat)

Uniprot ID

P11215 (Human); P05555 (Mouse)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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