Product
NeuroMab™ Mouse Anti-Human CD11b/CD11c Monoclonal Antibody (CBP2290)
[CAT#: NAB2010225LS]
Anti-CD11b/CD11c Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- FC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αx and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1, κ
Clone Number
CBP2290
Applications
FC
Application Notes
The optimal working dilutions shoµld be determined by the end user.
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation
Conjugation
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1686
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide and EDTA.
Concentration
1.0 mg/ml
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Endotoxin Level
Low Endotoxin
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Handling Advice
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
ITGAM; ITGAX
Official Name
ITGAM; ITGAX
Full Name
Integrin alpha M/Integrin, alpha X
Alternative Names
ITGAM; CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6; integrin subunit alpha M; ITGAX; CD11C; SLEB6; integrin subunit alpha X
References
1. Petty H. 1996. Immunol. Today 17:209.
2. Springer T. 1994. Cell 76:301.
3. Ihanus E, et al. 2007. Blood 109:802-810.
2. Springer T. 1994. Cell 76:301.
3. Ihanus E, et al. 2007. Blood 109:802-810.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
