Anti-Myelin CNPase Monoclonal Antibody (CBP3942)

[CAT#: NAB2012847LS]

Anti-Myelin CNPase Monoclonal Antibody [Alexa Fluor 647 ]

Host Species:: Mouse

Species Reactivity:: Human; Rat

Applications:: IHC-P

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Product Overview

Description

CNPase accounts for roughly 4% of the total myelin protein in the central nervous system (CNS). CNPase binds to tubulin heterodimers and plays a role in tubulin polymerization, and oligodendrocyte process outgrowth. The dimer consists of a varied proportion of CNP1 (46 kD) and CNP2 (48 kD) subunits in various species.

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP3942

Applications

IHC-P

Application Notes

IHC-P (5.0-10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Alexa Fluor 594; Alexa Fluor 488; Alexa Fluor 498; Alexa Fluor 647; Alexa Fluor 700; APC; APC/Cyanine 7; APC/Fire 750; Biotin; Brilliant Violet 421; Brilliant Violet 510; Brilliant Violet 570; Brilliant Violet 570; Brilliant Violet 605; Brilliant Violet 650; Brilliant Violet 711; Brilliant Violet 750; Brilliant Violet 785; FITC; HRP; PE; Pacific Blue; PE/Cyanine 5; PE/Cyanine 7; PerCP; Spark YG 570

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

Myelin CNPase

Official Name

CNP

Full Name

Myelin CNPase

Alternative Names

Tau 210-230

Gene ID

1267 (Human); 12799 (Mouse); 25275 (Rat)

References

1. Han H, et al. 2013. Biofactors. 39(3):233.
2. Raasakka A, et al. 2014. Neurosci Bull. 30(6):956.
3. Kim JY, et al. 2003. J. Neurosci. 23(13):5561-5571.
4. Sprinkle TJ, et al. 1989. Crit. Rev. Neurobiol. 4:235-301.
5. Ding BS, et al. 2013. PLoS One 8:e62150.
6. Ferletta M, et al. 2011. Int. J. Cancer 129:45.

Publications