Mouse Anti-Histone H3 (CBP4310)

[CAT#: NAB210183LS]

Anti-Histone H3 (C-terminus) Monoclonal Antibody [Alexa Fluor 594 ]

Host Species:: Mouse

Species Reactivity:: Human; Rat; Drosophila

Applications:: iCC; IHC-F; IHC-P

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Request Pricing

Inquiry

Product Overview

Description

Histone proteins are classified into core histones (H2A, H2B, H3, H4) and linker histones (H1, H5). Core histones form an octamer, which contains two H2A-H2B dimers and one H3-H4 tetramer. Core histones are predominantly globular except for the unstructured N-terminal tails. Posttranslational modifications, such as acetylation, methylation, phosphorylation, ubiquitination, SUMOylation and ADP-ribosylation occur in histone tails.

Immunogen

A peptide sequence derived from the C-terminal domain of human Histone H3 protein.

Species Reactivity

Human; Rat; Drosophila

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG3

Clone Number

CBP4310

Applications

iCC; IHC-F; IHC-P

Application Notes

ICC ( 1.25-5 µg/mL); IHC-F ( 2.5-10 µg/mL); IHC-P ( 1.25-5 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Alexa Fluor 594

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

Histone H3 (C-terminus)

Official Name

H3F3

Full Name

Histone H3

Alternative Names

H3-3A; H3.3A; H3F3; H3 histone; family 3A; H3 histone family member 3A; H3.3 histone A; H3F3A; H3-3B; H3-3B; H3.3B; H3 histone; family 3B (H3.3B); H3 histone family member 3B; H3.3 histone B; H3F3B; H3-3A

Publications