Mouse Anti-SATB2 Monoclonal Antibody (CBP6750)

Description

The development of the central nervous system includes the development of the brain, spinal cord, optic nerve and auditory system. In the neural tube, stem cells produce two major types The cells that make up most of the nervous system: neurons and glia. Both types of cells differentiate into many different types with highly specialized functions and shapes. The development of the peripheral and central nervous system begins in the early stages of embryogenesis and can be tracked by using lineage antibodies specific to each stage of neuron development. This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromatin remodeling. Defects in this gene are associated with isolated cleft palate and cognitive disability. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Feb 2010]

Epitope

Binds to an located within the peptide sequence SLGKTNEQSPHSQIH

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP6750

Applications

IHC; WB; IF

Application Notes

IHC: 1:500-1:1000
WB: 1 µg/ml
IF: 2-10 µg/ml

Research Areas

Growth and Development

Form

Liquid

Formulation

PBS, pH 7.2, 40% glycerol

Preservatives

0.02% Sodium azide

Concentration

0.1 mg/ml

Purification

Protein A purified

Shipping

Gel Pack

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling Advice

The antibody solution should be gently mixed before use.

Research Use Only

For research use only

Target

SATB2

Official Name

SATB2

Full Name

SATB Homeobox 2

Alternative Names

SATB Homeobox 2; Special AT-Rich Sequence-Binding Protein 2; SATB Family Member 2; DNA-Binding Protein SATB2; KIAA1034; GLSS

Gene ID

23314(Human); 212712(Mouse); 501145(Rat)

Uniprot ID

Q9UPW6(Human); Q8VI24(Mouse)