Human CHO-K1/ADRA2C/Gα15 Stable Cell Line

[CAT#: NCL20120022CR]

ADRA2C Adrenoceptors Stable Cell Line

Species:: Human

Applications:: GPCR Screening

Cell Types:: Other Cells

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Product Overview

Description

The adrenoceptors ADRA2C is expressed in the brain, kidney, aorta, lung, skeletal muscle, heart and spleen. ADRA2C knockout mice exhibited disrupts presynaptic inhibition of noradrenaline release at low stimulation frequencies.

Cell Types

Other Cells

Applications

GPCR Screening

Research Areas

GPCR; Neural Signal Transduction

Species

Human

Properties

Size

>1x10^6 Cells

Form

Frozen cells

Culture Medium

Ham's F12, 10% FBS, 400 μg/ml G418, 100 μg/ml Hygromycin B

Freeze Medium

45% culture medium, 45% FBS, 10% DMSO

Receptor

ADRA2C

Family

Adrenoceptors

Strain

ADRA2C/Gα15 Cell Line

Cell Purity

>95%

Shipping

Dry ice

Storage

Liquid nitrogen immediately upon delivery

Handling Advice

Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Warnings

Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents.

Target Details

Target

ADRA2C

Official Name

ADRA2C

Alternative Names

Alpha-2C adrenoceptor; Alpha 2-C4; adrenergic; alpha-2C; Adrenergic alpha 2C- receptor class I; alpha 2c; alpha-2 adrenergic receptor subtype C4; alpha-2C adrenergic receptor; alpha-2C adrenoceptor; alpha-2C adrenoreceptor; alpha-2CAR; subtype alpha2-C4; alpha2-C4; alpha2C; [a]2C; Adra-2c

Gene ID

151(Human); 11552(Mouse); 24174(Rat)

Uniprot ID

P18089(Human); P30545(Mouse); P19328(Rat)

References

1. Mi, G., Liu, S., Zhang, J., Liang, H., Gao, Y., Li, N.,.. & Yang, Z. (2017). Levo-tetrahydroberberrubine produces anxiolytic-like effects in mice through the 5-HT 1A receptor. PloS one, 12(1), e0168964.

Publications