Product
Human CHO-K1/D2/Gα15 Stable Cell Line
[CAT#: NCL20120053CR]
D2 Dopamine Receptor Stable Cell Line
- Species:
- Human
- Applications:
- GPCR Screening
- Cell Types:
- CHO-K1; GPCR Cell
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Overview
Description
It plays multiple roles in the periphery as a modulator of cardiovascular function, catecholamine release, hormone secretion, vascular tone, renal function, and gastrointestinal motility. The dopamine receptor family consists of five members, which are classified into two groups, D1-like (D1 and D5) and D2-like (D2, D3, and D4). Dopamine receptor 2 is mainly expressed in the brain. It has splicing variants, D2L and D2S. D2R receptor is implicated in a number of neurological and psychiatric conditions.
Cell Types
CHO-K1; GPCR Cell
Applications
GPCR Screening
Research Areas
GPCR; Neural Signal Transduction
Species
Human
Properties
Size
>1x10^6 Cells
Form
Frozen cells
Culture Medium
Ham's F12, 10% FBS, 200 μg/ml Zeocin,100 μg/ml Hygromycin B
Freeze Medium
45% culture medium, 45% FBS, 10% DMSO
Receptor
D2
Family
Dopamine receptor
Strain
D2/Gα15 Cell Line
Cell Purity
>95%
Shipping
Dry ice
Storage
Liquid nitrogen immediately upon delivery
Handling Advice
Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.
repeated exposure.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Warnings
Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents.
Target Details
Target
D2
Official Name
D2
Alternative Names
D2 receptor; D2A and D2B; D2(415) and D2(444); dopamine D2 receptor; D(2) dopamine receptor; dopamine receptor 2; dopamine receptor D2; Drd-2; D2 receptor; D2R
References
1. Montagna, E., Crux, S., Luckner, M., Herber, J., Colombo, A. V., Marinković, P.,.. & Sgobio, C. (2019). In vivo Ca2+ imaging of astrocytic microdomains reveals a critical role of the amyloid precursor protein for mitochondria. Glia, 67(5), 985-998. 2. Xu, Y., Wu, X., Wang, S., Yang, C., Li, Y., & Cao, Y. (2019). Hydroxyapatite Nanoparticle-Crosslinked Peptide Hydrogels for Three-Dimensional Culture and Differentiation of MC3T3-E1 Osteoblasts. Journal of biomedical nanotechnology, 15(12), 2351-2362. 3. Lan, J., Rollins, J. A., Zang, X., Wu, D., Zou, L., Wang, Z.,.. & Chen, D. (2019). Translational regulation of non-autonomous mitochondrial stress response promotes longevity. Cell reports, 28(4), 1050-1062.
Publications
Publications (0)
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
