Human CHO-K1/TRH1 Stable Cell Line

[CAT#: NCL20120132CR]

TRH1 Thyrtropin-releasing Hormone Receptor Stable Cell Line

Species:: Human

Applications:: GPCR Screening

Cell Types:: Other Cells

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Product Overview

Description

It is a member of G-protein coupled receptor family A. This protein is a receptor for Thyrtropin-releasing hormone (TRH). Human TRH1 is expressed in lymphocytes, pituitary gland and CNS. It can stimulate the releasing of prolactin (PRL), thyrotropin (TSH). TRH1 receptor knockout mice exhibit a slightly reduced growth rate, considerable decrease in serum T3, T4, and prolactin levels but no alteration of thyroid-stimulating hormone levels.

Cell Types

Other Cells

Applications

GPCR Screening

Research Areas

GPCR

Species

Human

Properties

Size

>1x10^6 Cells

Form

Frozen cells

Culture Medium

Ham's F12, 10% FBS, 400 μg/ml G418

Freeze Medium

45% culture medium, 45% FBS, 10% DMSO

Receptor

TRH1/TRHR

Family

Thyrtropin releasing hormone receptor

Strain

TRH1 Cell Line

Cell Purity

>95%

Shipping

Dry ice

Storage

Liquid nitrogen immediately upon delivery

Handling Advice

Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Warnings

Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents.

Target Details

Target

TRH1

Official Name

TRH1

Alternative Names

TRH1 receptor; TRHR; TRH receptor; TRH-R; thyroliberin receptor; thyrotropin-releasing hormone receptor; TRH-R1

Gene ID

3269(Human); 15465(Mouse); 24448(Rat)

Uniprot ID

P35367(Human); P70174(Mouse); P31390(Rat)

References

1. Zhang, W., Chen, L., Ma, Z., Du, L., & Li, M. (2014). Design, synthesis and biological evaluation of naphthalimidebased fluorescent probes for α1-adrenergic receptors. Drug Discoveries & Therapeutics, 8(1), 11-17.

Publications