Human CXCR4 Gi Cell Line [CHO-K1]

[CAT#: NCL-7P578]

Species:: Human

Applications:: GPCR Screening

Cell Types:: Other Cells

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Product Overview

Description

The cAMP Gi cell line NCL-7P578 established by Creative Biolabs can overexpress natural Gi-coupled wild-type GPCRs. It has been used to detect the inhibition of intracellular cAMP production on receptor agonist stimulation.

Features

Tag: None
Agonist/Ligand: Recombinant Human SDF-1α (CXCL12)

Cell Types

Other Cells

Cell Location

cAMP

Applications

GPCR Screening

Assay

GPCR Screening Assay

Readout

cAMP

Assay Characteristics

Tag: None
Agonist/Ligand: Recombinant Human SDF-1α (CXCL12)

Species

Human

Properties

Shipping

Dry ice.

Storage

Liquid Nitrogen

Research Use Only

For research use only

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Target Details

Target

CXCR4

Official Name

CXCR4

Alternative Names

C-X-C chemokine receptor type 4; CD184; CD184 antigen; CXC-R4; CXCR-4; D2S201E; FB22; HM89; HSY3RR; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; SDF-1 receptor; WHIM; chemokine (C-X-C motif) receptor 4; chemokine (C-X-C motif); receptor 4 (fusin); fusin; leukocyte-derived seven transmembrane domain receptor; leukocyte-derived seven-transmembrane-domain receptor; lipopolysaccharide-associated protein 3; neuropeptide Y receptor Y3; seven transmembrane helix receptor; seven-transmembrane-segment receptor; spleen; stromal cell-derived factor 1 receptor

Publications