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Creative Biolabs

IonON™ Human Kv4.3/KChIP1 Recombinant Stable Cell Line

[CAT#: NCL-7P101]

Creative Biolabs provides numerous IonON cell models of ion channels to meet your drug discovery needs.

Species:
Human
Applications:
Ion Channel Assay
Cell Types:
Other Cells

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Product Overview

Description

The Kv4.3 subfamily of the Kv4 family is often referred to as KCND3. Human Ito's primary channel is Kv4.3, and the amount of the accessory protein KChIP2 is suggested to regulate regional variances in expression. The blocking of this channel may raise the risk of arrhythmia due to their critical involvement in regulating the trajectory of action potentials in diverse areas of the heart. KChIP1 and Kv4.3 often co-localize in interneurons in the cortex, hippocampus, and striatum. A cell line with physiological relevance is represented by this complex of Human Kv4.3 and KChIP1.

Cell Types

Other Cells

Applications

Ion Channel Assay

Application Notes

Electrophysiology assay (Conventional and automated patch clamp platforms)

Species

Human
Properties

Size

2 Vials of mycoplasma-free cells, 1 mL per vial aliquots containing 2M to 4M cells/mL in DMSO

Mycoplasma Testing

The cell line has been screened using the Mycoplasma Detection Kit to confirm the absence of Mycoplasma contamination.

Shipping

Dry ice.

Storage

Liquid Nitrogen

Research Use Only

For research use only

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Target Details

Target

Kv4.3/KChIP1

Official Name

KCND3

Alternative Names

KCND3; KCND3L; KCND3S; KSHIVB; KV4.3; SCA19; SCA22; BRGDA9; potassium voltage-gated channel subfamily D member 3
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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