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Creative Biolabs

NeuroMab™ Anti-Dopamine transporter BBB Shuttle Antibody(NRZP-1222-ZP1033)

[CAT#: NRZP-1222-ZP1033]

Host Species:
Mouse
Species Reactivity:
Drosophila
Applications:
In Vitro

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. Creative Biolabs has developed a BBB shuttle antibody platform that actively transports these large biomolecules across the BBB via receptor-mediated transcytosis (RMT). The engineered BBB shuttle antibody is believed to significantly increase the uptake of therapeutic molecules in the brain.

Species Reactivity

Drosophila

Host Species

Mouse

Applications

In Vitro

Relevant Diseases

Parkinson's Disease
Target

Target

Dopaminetransporter

Official Name

SLC6A3

Full Name

dopamine active transporter

Alternative Names

SLC6A3; solute carrier family 6 (neurotransmitter transporter); member 3; DAT; DAT1; PKDYS; solute carrier family 6 member 3; Dopamine transporter; PKDYS1
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