NeuroMab™ Anti-PSD-95 MAGUK scaffold protein BBB Shuttle Antibody, Clone K28/43
[CAT#: NRZP-0423-ZP355]
- Species Reactivity:
- Human; Rat; Mouse
- Applications:
- WB; IHC; IP; ICC
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-PSD 95 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 77-299 (PDZ domains 1 and 2) of human PSD-95 (also known as Postsynaptic density protein 95, Disks large homolog 4, Synapse-associated protein 90, DLG4, Dlgh4 and SAP-90, accession number P78352)
Rat: 100% identity (223/223 amino acids identical)
Mouse: 99% identity (221/223 amino acids identical)
65-80% identity with DLG1/SAP97,
DLG2/Chapsyn-110 and DLG3/SAP102
Rat: 100% identity (223/223 amino acids identical)
Mouse: 99% identity (221/223 amino acids identical)
65-80% identity with DLG1/SAP97,
DLG2/Chapsyn-110 and DLG3/SAP102
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human; Rat; Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
K28/43
Applications
WB; IHC; IP; ICC
Application Notes
Does not cross-react with DLG1/SAP97, DLG2/Chapsyn-110 or DLG3/SAP102
Research Areas
Scaffolds
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
PSD 95
Official Name
DLG4
Full Name
PSD-95
Alternative Names
DLG4; PSD95; SAP-90; SAP90; Dlgh4; PSD-95; SAP90A; discs large homolog 4; discs large MAGUK scaffold protein 4; MRD62
Uniprot ID
P78352
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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