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Creative Biolabs

Anti-PSD 95 Monoclonal Antibody (CBP3885)

[CAT#: NAB2012447LS]

Anti-PSD 95 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human; Rat
Applications:
WB; IHC-P

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Product Overview

Description

PSD95, also known as SAP-90, is a member of the MAGUK family, encoded by the the DLG4 gene. At postsynaptic sites, it mediates the scaffolding of NMDA receptors, AMPA receptors, potassium channels, and other associated signaling protein clusters. It plays an important role in synaptic plasticity and the stabilization of synaptic changes during long-term potentiation.

Immunogen

This monoclonal antibody was raised against a fusion protein corresponding to amino acids 77-299 (PDZ domains 1 and 2) of human PSD-95.

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP3885

Applications

WB; IHC-P

Application Notes

WB (0.1- 5.0 µg/ml); IHC-P (2.0- 10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

PSD 95

Official Name

DLG4

Full Name

Postsynaptic density protein 95

Alternative Names

DLG4; PSD95; SAP-90; SAP90; Dlgh4; PSD-95; SAP90A; discs large homolog 4; discs large MAGUK scaffold protein 4; MRD62

Gene ID

1742 (Human); 13385 (Mouse)

Uniprot ID

P78352 (Human); Q62108 (Mouse)
Publications

Publications (0)

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