NeuroMab™ Anti-SPP1 Antibody(NRP-0422-P694)

Product Overview

Description

The anti-human OPN antibody is capable of treating ovarian cancer cell and lung carcinoma cell.

Species Reactivity

Human; Mouse

Clonality

Monoclonal

Host Species

Mouse

Clone Number

NR477P

Applications

WB; Inhihb; ELISA; In Vitro; In Vivo

Relevant Diseases

Alzheimer's Disease; Neuroinflammation

Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

>95% by SDS PAGE or HPLC

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only

Target

SPP1

Official Name

SPP1

Full Name

Secreted phosphoprotein 1

Alternative Names

BNSP;
Bone sialoprotein 1;
Bone sialoprotein I;
BSP I;
BSPI;
Early T lymphocyte activation 1;
ETA 1;
ETA1;
MGC110940;
Nephropontin;
OPN;
Osteopontin;

Gene ID

6696(Human)

Uniprot ID

P10451(Human)

Product Pictures

SDS-PAGE

Figure 1 shows the results of SDS-PAGE electrophoresis detection of OPN truncated expression.

EC50 values were calculated from a 4 parameter fit equation using Prism Graphpad using the data from Figure 10. A2=2.6 ng/ml, A6=3.2 ng/ml; E5=4.0 ng/ml, G7=93.2 ng/ml.

ELISA

Figure 2 shows the results of measuring the affinity and truncation of the anti-OPN chimeric antibody.

EC50 values were calculated from a 4 parameter fit equation using Prism Graphpad using the data from Figure 10. A2=2.6 ng/ml, A6=3.2 ng/ml; E5=4.0 ng/ml, G7=93.2 ng/ml.

Publications