CD8+/OPN Therapeutic Aptamer (4-1BB-OPN)

[CAT#: NV-2106-P76]

Target:: SPP1

Product Type:: Aptamers

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Product Overview

Description

Aptamer Role: Agonist/antagonist
SELEX Method: SELEX primer/in vitro SELEX
KD (nmol/L): 40/18
Composition: 2'-Fluoro RNA/RNA
Therapeutic Application: CD8+ T cell activation/block M0 and M2

Properties

Research Use Only

This product is for research use only.

Target Details

Target

SPP1

Official Name

SPP1

Full Name

Secreted phosphoprotein 1

Alternative Names

BNSP;
Bone sialoprotein 1;
Bone sialoprotein I;
BSP I;
BSPI;
Early T lymphocyte activation 1;
ETA 1;
ETA1;
MGC110940;
Nephropontin;
OPN;
Osteopontin;

Gene ID

6696(Human)

Uniprot ID

P10451(Human)

References

Wei, J., Marisetty, A., Schrand, B., Gabrusiewicz, K., Hashimoto, Y., Ott, M., ... & Heimberger, A. B. (2019). Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target. The Journal of clinical investigation, 129(1), 137-149.
under Open Access license CC BY 4.0, without modification.

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