Product
NeuroMab™ Mouse Anti-CD36 Monoclonal Antibody (CBP2581)
[CAT#: NAB2007FY1061]
Mouse Monoclonal [SMNS] to CD36
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- FC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
Mouse anti-human CD36 antibody, recognizes CD36 antigen, a cell surface glycoprotein of approximately 88 kDa, expressed by platelets, monocytes/macrophages, and some microvascular endothelial and erythroid precursors. CD36 is the receptor for thrombospondin. When expressed by monocytes and macrophages, CD36 acts as a receptor for oxidized LDL and apoptotic polymorphonuclear cells. Mouse anti-human CD36 antibody, clone SMØ, partially inhibits collagen-induced platelet aggregation and macrophages uptake of apoptotic neutrophils. According to reports, this antibody can activate platelets through fibrinogen binding, P-selectin expression and annexin V binding-for more details, please contact our technical service team.
Immunogen
Human tonsil cells and peripheral blood mononuclear cells.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgM
Clone Number
CBP2581
Applications
FC
Application Notes
FC: 1/5-1/10
Relevant Diseases
Alzheimer's Disease; Neurodegenerative Disease
Research Areas
Neuroregeneration
Conjugation
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1877
Product Properties
Form
Liquid
Formulation
PBS, 0.09% Sodium Azide, 1% BSA
Preservatives
YES
Concentration
0.05 mg/ml
Endotoxin Level
Low Endotoxin
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at +4°C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend micr°Centrifugation before use.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
CD36
Official Name
CD36
Full Name
CD36 Molecule
Alternative Names
CD36 Molecule; CD36 Antigen (Collagen Type I Receptor, Thrombospondin Receptor); CD36 Molecule (Thrombospondin Receptor); Leukocyte Differentiation Antigen CD36; Platelet Glycoprotein IV; Fatty Acid Translocase; Glycoprotein IIIb; PAS IV; GPIIIB; GP3B; GPIV; FAT; GP4;
References
1. Sarigianni, M. et al. (2010) Effect of leptin and insulin resistance on properties of human monocytes in lean and obese healthy participants.
2. Sugihara, K. et al. (1992) Thrombospondin mediates adherence of CD36+ sickle reticulocytes to endothelial cells.
3. Biswas, A.K. et al. (2007) Plasmodium falciparum uses gC1qR/HABP1/p32 as a receptor to bind to vascular endothelium and for platelet-mediated clumping.
4. Pain, A. et al. (2001) Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malaria.
2. Sugihara, K. et al. (1992) Thrombospondin mediates adherence of CD36+ sickle reticulocytes to endothelial cells.
3. Biswas, A.K. et al. (2007) Plasmodium falciparum uses gC1qR/HABP1/p32 as a receptor to bind to vascular endothelium and for platelet-mediated clumping.
4. Pain, A. et al. (2001) Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malaria.
Publications
Publications (0)
Neural Antibodies
Kits
For Research Use Only. Not For Clinical Use.
