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Creative Biolabs

Mouse Anti-CD11c Monoclonal Antibody (CBP4331)

[CAT#: NAB2101110LS]

Anti-CD11c Monoclonal Antibody [Alexa Fluor 488 ]

Host Species:
Mouse
Species Reactivity:
Human; African green monkey; Baboon; Chimpanzee; Cynomolgus; Rhesus; Squirrel Monkey
Applications:
FC

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Product Overview

Description

CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αX and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.

Species Reactivity

Human; African green monkey; Baboon; Chimpanzee; Cynomolgus; Rhesus; Squirrel Monkey

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP4331

Applications

FC

Application Notes

FCM (5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Alexa Fluor 488
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

Batch Dependent

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

CD11c

Official Name

ITGAX

Full Name

Integrin alpha X

Alternative Names

ITGAX; CD11C; SLEB6; integrin subunit alpha X

Gene ID

3687 (Human); 16411 (Mouse)

Uniprot ID

P20702 (Human); Q9QXH4 (Mouse)
Publications

Publications (0)

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