Mouse Anti-Armenian Hamster CD11c Monoclonal Antibody (CBP3657)

[CAT#: NAB2012364LS]

Anti-CD11c Monoclonal Antibody [APC]

Host Species:: Mouse

Species Reactivity:: Armenian Hamster

Applications:: FC

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Product Overview

Description

CD11c is a 150 kD glycoprotein, also known as αX integrin, CR4 and p150. CD11c and β2 integrin (CD18) form an αXβ2 heterodimer. It is mainly expressed on dendritic cells, NK cells, a part of intestinal intraepithelial lymphocytes (IEL) and some activated T cells. αXβ2 integrin plays an important role in cell-cell contact by binding to its ligand iC3b, fibrinogen and CD54.

Immunogen

Mouse spleen dendritic cells

Species Reactivity

Armenian Hamster

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG

Clone Number

CBP3657

Applications

Application Notes

FCM (≤ 0.5 µg per 106 cells in 100 µL volume)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Alexa Fluor 594; Alexa Fluor 488; Alexa Fluor 498; Alexa Fluor 647; Alexa Fluor 700; APC; APC/Cyanine 7; APC/Fire 750; Biotin; Brilliant Violet 421; Brilliant Violet 510; Brilliant Violet 570; Brilliant Violet 570; Brilliant Violet 605; Brilliant Violet 650; Brilliant Violet 711; Brilliant Violet 750; Brilliant Violet 785; FITC; HRP; PE; Pacific Blue; PE/Cyanine 5; PE/Cyanine 7; PerCP; Spark YG 570

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

CD11c

Official Name

ITGAX

Full Name

Integrin alpha X

Alternative Names

ITGAX; CD11C; SLEB6; integrin subunit alpha X

Gene ID

3687 (Human); 16411 (Mouse)

Uniprot ID

P20702 (Human); Q9QXH4 (Mouse)

References

1. Barclay A, et al. 1997. The Leukocyte Antigen Facts Book Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Lopez-Rodriguez C, et al. 1996. J. Immunol. 156:3780.

Publications