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Creative Biolabs
Product

NeuroMab™ Anti-Pan-SAPAP, Clone N127/31 (CBP8434)

[CAT#: NRP-0422-P333]

Species Reactivity:
Human; Rat; Mouse
Applications:
WB; IHC; ICC

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Product Overview

Immunogen

Fusion protein amino acids 772-992 (C-terminus) of rat SAPAP1 (also known as disks large-associated protein 1, guanylate kinase-associated protein, GKAP, SAP90/PSD-95-associated/binding protein 1, accession number P97836)
Mouse: 99% identity (200/201 amino acids identical)
Human: 99% identity (199/201 amino acids identical) 55-65% identity with other SAPAPs

Species Reactivity

Human; Rat; Mouse

Clonality

Monoclonal

Isotype

IgG2b

Clone Number

CBP8434

Applications

WB; IHC; ICC

Application Notes

Cross-reacts with other SAPAPs

Research Areas

Scaffolds

Conjugation

Unconjugated
Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.
Target

Target

SAPAP

Official Name

Pan-SAPAP

Full Name

Pan-SAPAP

Alternative Names

Synapse-Associated Protein 90/Postsynaptic Density-95-Associated Protein
Product Pictures
IB

Fig. 1 Immunoblots on membranes prepared from whole mouse (MBM) and rat (RBM) brain, and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)], and cerebellum [HBM(Cb)].

IB

Fig. 2 Adult RBM and transfected cell immunoblot: extracts of RBM and COS cells transiently transfected with Flag-tagged SAPAP1, SAPAP4 or untagged Kv2.1 plasmids and probed with N127/31 TC supe.

IF

Fig. 3 Cultured rat hippocampal pyramidal cell (left) and interneuron (right) immunofluorescence staining. N127/31 (Pan-SAPAP)=green, rabbit anti-PSD-95=red.

IHC

Fig. 4 Adult rat hippocampus immunohistochemistry.

IB

Fig. 5 Adult rat brain membrane (RBM) immunoblot.

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