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Creative Biolabs

Anti-SAPAP Monoclonal Antibody (CBP4003)

[CAT#: NAB20121012LS]

Anti-SAPAP Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human; Rat
Applications:
WB

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Product Overview

Description

SAPAP is also known as DAP-1 or GKAP, encoded by the DLGAP1 gene. It is enriched in the postsynaptic membrane and is responsible for connecting PSD-95 and SHANK, which serves as an adapter protein that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton.

Immunogen

This monoclonal antibody was raised against a fusion protein corresponding to amino acids 772-992 (C-terminus) of rat SAPAP1.

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP4003

Applications

WB

Application Notes

WB (2.0-10.0 µg/nL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

SAPAP

Official Name

Pan-SAPAP

Full Name

Synapse-Associated Protein 90/Postsynaptic Density-95-Associated Protein

Alternative Names

Synapse-Associated Protein 90/Postsynaptic Density-95-Associated Protein

Gene ID

58512(Human); 242667(Mouse); 286923(Rat)

Uniprot ID

O95886(Human); Q6PFD5(Mouse); P97838(Rat)
Publications

Publications (0)

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