Rat Microglia, Neonatal
Positive for F4/80 and CD11b/c
Microglia originate from hematopoietic stem cells in the bone marrow and are resident macrophages in the central nervous system (CNS). Due to the presence of the blood-brain barrier, they are separated from the rest of the body. Microglia actively investigate the surrounding area and respond by removing damaged nerve cells, plaques and infectious agents. Since microglia have the function of immune response and maintenance of homeostasis in the central nervous system, they are related to neurodevelopment, central nervous system plasticity and repair, neuroinflammation, aging and neurodegeneration, neuropathic pain and infection.
Genetic Stability Testing
Growing cells: Growing cell cultures should be checked on receipt using an inverted microscope. Immediately check the cell density upon arrival for any obvious defects. If the cell density is too high (more than 80% confluent) subculture the cells (harvest and reseed) immediately.
For detailed instructions on the thawing procedure of frozen cells and the culture of adherent or suspended cells, please feel free to contact us by email or phone.