Product
NeuCELL™ VM Human Neural Progenitor Cell Line, Immortalized
[CAT#: NCL-2108-P002]
NeuCELL™ VM is an immortalized human neural progenitor cell line with the ability to readily differentiate into neurons & glial cells.
- Species:
- Human
- Applications:
- Cell Culture
- Cell Types:
- Neural Stem Cell; Neural Progenitor Cell
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Overview
Description
An immortalised cell line of human neural progenitors called NeuCELL™ VM may easily develop into neurons and glial cells. The ventral mesencephalon of the foetal human brain served as the source of NeuCELL™ VM. The v-myc oncogene was immortalised by retroviral transduction, and this cell line grows quickly as a monolayer on laminin with a doubling period of 20-30 hours. According to karyotype investigations, the NeuCELL™ VM maintains a typical diploid karyotype in culture even after numerous passages (more than 45 passages). Furthermore, it has been demonstrated that neurons derived from NeuCELL™ VM are electophysiologically active. Numerous research projects can make use of NeuCELL™ VM, including investigations into neurotoxicity, neurogenesis, electrophysiology, and the actions of neurotransmitters and receptors.
Cell Types
Neural Stem Cell; Neural Progenitor Cell
Applications
Cell Culture
Application Notes
NeuCELL™ can be used in a 3D cell model of Alzheimer's Disease!
Species
Human
Properties
Size
>1x10^6 Cells
Tissue Source
Human ventral mesencephalon brain tissue
Shipping
Dry ice.
Storage
Liquid Nitrogen
Research Use Only
For research use only
Quality Control
Each lot of NeuCELL™ cells has been validated for high level of expression of Nestin and Sox 2 and for their self-renewal and multi-lineage differentiation capacities. Cells also display normal karyotype as assessed by chromosome spread and tested negative for mycoplasma. Maternal blood has been screened for HIV, HTLV, Hepatitis B and C.
Publications
Publications (0)
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
