Creative Biolabs

NeuCELL™ VM Human Neural Progenitor Cell Line, Immortalized

[CAT#: NCL-2108-P002]

NeuCELL™ VM is an immortalized human neural progenitor cell line with the ability to readily differentiate into neurons & glial cells.

Species:
Human
Applications:
Cell Culture
Cell Types:
Neural Stem Cell; Neural Progenitor Cell

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Description
NeuCELL™ VM is an immortalized human neural progenitor cell line with the ability to readily differentiate into neurons and glial cells. NeuCELL™ VM was derived from the ventral mesencephalon region of human fetal brain. Immortalized by retroviral transduction with the v-myc oncogene, this cell line grows rapidly as a monolayer on laminin with a doubling time of 20-30 hours. Karyotype analyses indicate that the NeuCELL™ VM retains a normal diploid karyotype in culture even after prolonged passage (>45 passages). Neurons differentiated from NeuCELL™ VM have furthermore been shown to be electophysiologically active. NeuCELL™ VM may be used for a variety of research applications such as studies of neurotoxicity, neurogenesis, electrophysiology, neurotransmitter and receptor functions.
Cell Types
Neural Stem Cell; Neural Progenitor Cell
Applications
Cell Culture
Application Notes
NeuCELL™ can be used in a 3D cell model of Alzheimer's Disease!
Species
Human
Size
1 vial
Tissue Source
Human ventral mesencephalon brain tissue
Shipping
Dry ice.
Storage
Liquid Nitrogen
Research Use Only
For research use only
Quality Control
Each lot of NeuCELL™ cells has been validated for high level of expression of Nestin and Sox 2 and for their self-renewal and multi-lineage differentiation capacities. Cells also display normal karyotype as assessed by chromosome spread and tested negative for mycoplasma. Maternal blood has been screened for HIV, HTLV, Hepatitis B and C.
For Research Use Only. Not For Clinical Use.
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