NeuroMab™ Anti-SynDIG1/Tmem90b BBB Shuttle Antibody, Clone L42/17
[CAT#: NRZP-0423-ZP415]
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB; IHC; ICC
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-SynDIG1 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 1-183 (cytoplasmic N-terminus) of mouse SynDIG1 (also known as Synapse differentiation-inducing gene protein 1, Dispanin subfamily C member 2, Transmembrane protein 90B, DSPC2, Tmem90b and C20orf39, accession number A2ANU3)
Rat: 97% identity (179/183 amino acids identical)
Human: 91% identity (167/183 amino acids identical)
<50% identity with SynDIG1L/SynDIG2/Capucin/Tmem90a
Rat: 97% identity (179/183 amino acids identical)
Human: 91% identity (167/183 amino acids identical)
<50% identity with SynDIG1L/SynDIG2/Capucin/Tmem90a
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
L42/17
Applications
WB; IHC; ICC
Research Areas
CAMs
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
SynDIG1
Official Name
SYNDIG1
Full Name
SynDIG1/Tmem90b
Alternative Names
SynDIG1
Uniprot ID
A2ANU3
Product Pictures
IB
Fig. 1 Adult rat brain membrane immunoblot.
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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