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Creative Biolabs

NeuroMab™ Anti-Notch1 Antibody, Clone N6640 (CBP14859)

[CAT#: NRZP-0922-ZP3548]

Host Species:
Rat
Species Reactivity:
Human; Mouse; Rat; Bovine
Applications:
WB; IP

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Product Overview

Description

The NeuroMab™ anti-Notch1 antibody detects endogenous levels of total Notch1 protein. It recognizes both the full-length (~ 300 kDa) protein and the transmembrane/intracellular region NTM (~120 kDa), which consists of a short extracellular juxtamembrane peptide, a transmembrane sequence and the intracellular domain (NICD). The antibody cannot detect the extracellular (ligand-binding) domain of Notch1 following cleavage at the S2 site by ADAM-type metalloproteases.

Expression Host

Monoclonal antibody is produced by immunizing animals with a fusion protein corresponding to intracellular residues of Notch1.

Species Reactivity

Human; Mouse; Rat; Bovine

Clonality

Monoclonal

Host Species

Rat

Isotype

Rat IgG2b

Clone Number

CBP14859

Applications

WB; IP
Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only
Target

Target

NOTCH1

Official Name

NOTCH1

Full Name

Notch1

Alternative Names

AOVD1; Translocation-associated notch protein TAN-1; NEXT; hN1; AOS5; NICD; Notch 1; Neurogenic locus notch homolog protein 1; TAN1

Gene ID

4851(Human)

Uniprot ID

P46531(Human)
Publications

Publications (0)

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