NeuroMab™ Anti-Notch1 Antibody, Clone N16006 (CBP14858)
[CAT#: NRZP-0922-ZP3547]
- Host Species:
- Rabbit
- Species Reactivity:
- Human
- Applications:
- WB; IP
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SPECIFIC INQUIRY
inquiryProduct Overview
Description
The NeuroMab™ anti-Notch1 antibody detects intracellular epitopes between 2400 and 2500 amino acids of human Notch1. It recognizes both the full-length (~300 KDa) and the NTM region (~120 KDa), which consists of a short extracellular juxtamembrane peptide, a transmembrane sequence and the intracellular domain (NICD). The antibody cannot detect the extracellular (ligand-binding) domain of Notch1 following cleavage at the S2 site by ADAM-type metalloproteases.
Expression Host
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gln2501 of human Notch1.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Rabbit
Isotype
Rabbit
Clone Number
CBP14858
Applications
WB; IP
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Publications
Publications (0)
Neural Cell Lines
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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