Product
NeuroMab™ Mouse Anti-CD14 Monoclonal Antibody (CBP1940)
[CAT#: NAB2007FY386]
Mouse Monoclonal [W0038] to CD14
- Host Species:
- Mouse
- Species Reactivity:
- Bovine; Sheep; Human; Water Buffalo
- Applications:
- FC
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
Mouse anti-bovine CD14 clone CC-G33 is a monoclonal antibody that recognizes bovine CD14. Bovine CD14 is a GPI-anchored membrane glycoprotein and monocyte/macrophage differentiation antigen. It belongs to the family of lipopolysaccharide receptors and is found in microglia. It is also weakly expressed on cells and Langerhans cells.
CD14 acts as a receptor for effective bacterial endotoxin lipopolysaccharide (LPS) and is promoted by LPS binding protein (LBP). The binding of LPS to CD14 leads to cell activation, cytokine release and inflammatory response, and has been shown to upregulate the cell surface expression of adhesion molecules.
CD14 acts as a receptor for effective bacterial endotoxin lipopolysaccharide (LPS) and is promoted by LPS binding protein (LBP). The binding of LPS to CD14 leads to cell activation, cytokine release and inflammatory response, and has been shown to upregulate the cell surface expression of adhesion molecules.
Immunogen
Partially purified polypeptide isolated from the surface membrane of bovine leukocytes.
Species Reactivity
Bovine; Sheep; Human; Water Buffalo
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP1940
Applications
FC
Relevant Diseases
Lou Gehring's Disease
Research Areas
Neuroregeneration
Conjugation
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1575
Product Properties
Form
Liquid
Formulation
PBS; 0.09% Sodium Azide
1% Bovine Serum Albumin
1% Bovine Serum Albumin
Preservatives
Yes
Concentration
0.1 mg/ml
Purification
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
Endotoxin Level
Low Endotoxin
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at +4°C or at -20°C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
References
1. Berthon, P. & Hopkins, J. (1996) Ruminant cluster CD14.
2. Glew, E.J. et al. (2003) Differential effects of bovine viral diarrhoea virus on monocytes and dendritic cells.
3. Harris, J. et al. (2003) Expression of caveolin by bovine lymphocytes and antigen-presenting cells.
4. Yamakawa, Y. et al. (2008) Identification and functional characterization of a bovine orthologue to DC-SIGN.
5. Herath, S. et al. (2006) Expression and function of Toll-like receptor 4 in the endometrial cells of the uterus.
6. Gliddon, D.R. et al. (2004) DEC-205 expression on migrating dendritic cells in afferent lymph.
2. Glew, E.J. et al. (2003) Differential effects of bovine viral diarrhoea virus on monocytes and dendritic cells.
3. Harris, J. et al. (2003) Expression of caveolin by bovine lymphocytes and antigen-presenting cells.
4. Yamakawa, Y. et al. (2008) Identification and functional characterization of a bovine orthologue to DC-SIGN.
5. Herath, S. et al. (2006) Expression and function of Toll-like receptor 4 in the endometrial cells of the uterus.
6. Gliddon, D.R. et al. (2004) DEC-205 expression on migrating dendritic cells in afferent lymph.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
