Mouse Anti-CD14 Monoclonal Antibody (CBP1938)
[CAT#: NAB2007FY384]
Mouse Monoclonal [AV141] to CD14
- Host Species:
- Mouse
- Species Reactivity:
- Chicken
- Applications:
- ELISA; WB
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
Mouse anti-chicken CD14 antibody, clone AV141 recognizes chicken monocyte differentiation antigen CD14, a GPI-anchored membrane glycoprotein containing 465 amino acids. CD14 is a monocyte/macrophage differentiation antigen, belonging to the lipopolysaccharide receptor family, and is also weakly expressed on microglia and Langerhans cells.
CD14 acts as a receptor for effective bacterial endotoxin lipopolysaccharide (LPS) and is promoted by LPS binding protein (LBP). The binding of LPS to CD14 leads to cell activation, cytokine release and inflammatory response, and has been shown to upregulate the cell surface expression of adhesion molecules.
Clone AV141 is one of a series of antibodies developed by the Roslin Institute as part of the Avian Immunization Toolbox project.
CD14 acts as a receptor for effective bacterial endotoxin lipopolysaccharide (LPS) and is promoted by LPS binding protein (LBP). The binding of LPS to CD14 leads to cell activation, cytokine release and inflammatory response, and has been shown to upregulate the cell surface expression of adhesion molecules.
Clone AV141 is one of a series of antibodies developed by the Roslin Institute as part of the Avian Immunization Toolbox project.
Immunogen
Chicken CD14/huIg fusion protein.
Species Reactivity
Chicken
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP1938
Applications
ELISA; WB
Relevant Diseases
Lou Gehring's Disease
Research Areas
Neuroregeneration
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS; 0.09% Sodium Azide
Preservatives
Yes
Concentration
1.0 mg/ml
Purification
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at +4°C or at -20°C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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