NeuroMab™ Mouse Anti-CD205 Monoclonal Antibody (CBP2571)
[CAT#: NAB2007FY1019]
Mouse Monoclonal [HD30] to CD205
- Host Species:
- Mouse
- Species Reactivity:
- Human; Monkey
- Applications:
- FC; IHC-Fr; WB
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
Mouse anti-human CD205 antibody, recognizes human lymphocyte antigen 75, also known as CD205, DEC205, C-type lectin domain family 13 member B or gp200-MR6. CD205 is a 1695 amino acid, about ~205 kDa single type I transmembrane glycoprotein, a member of the macrophage mannose receptor family of C-type lectins, and is mainly expressed by human dendritic cells. CD205 is a recycled endocytic receptor, involved in directing antigen uptake for the processing and presentation of MHC class I. Various isoforms of human CD205 produced by alternative splicing have been described. Mouse anti-human CD205 antibody, recognizes canonical isoform 4, and the reactivity with other isoforms has not been evaluated, but both isoforms 2 and 3 contain most of the immunogenic sequences used to generate clone HD30, so it is very May be reactive. However, the antibody is not expected to react with isotypes 1 and 5 that lack the immunogen sequence.
Species Reactivity
Human; Monkey
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP2571
Applications
FC; IHC-Fr; WB
Application Notes
FC: 1/10-1/200
Relevant Diseases
Alzheimer's Disease; Neurodegenerative Disease
Research Areas
Neuroregeneration
Conjugation
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1871
Product Properties
Form
Liquid
Formulation
PBS
Preservatives
BSA free
Concentration
1 mg/ml
Purification
Protein G
Endotoxin Level
Low Endotoxin
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at -20°C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend micr°Centrifugation before use.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
References
1. Park, C.G. et al. (2012) Generation of anti-human DEC205/CD205 monoclonal antibodies that recognize epitopes conserved in different mammals.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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