Mouse Anti-CD205 Monoclonal Antibody (CBP2569)

Product Overview

Description

Mouse anti-bovine CD205 antibody, recognizes the surface antigen of bovine CD205 cells, which is a ~210-220 kDa molecule expressed by CD2 + ve but not WC1 + ve T cells. CD205 is also expressed by B cells and weakly stains B cell follicles. Bovine CD205 has previously been described as the WC6 antigen (Gliddon et al., 2004).

Species Reactivity

Bovine; Sheep

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b

Clone Number

CBP2569

Applications

FC; IHC-Fr; IP

Application Notes

FC: 1/50-1/200

Relevant Diseases

Alzheimer's Disease; Neurodegenerative Disease

Research Areas

Neuroregeneration

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.09% Sodium Azide

Preservatives

YES

Concentration

1 mg/ml

Purification

Protein G

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at +4°C or at -20°C if preferred. This product should be stored undiluted.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

CD205

Official Name

LY75

Full Name

lymphocyte antigen 75

Alternative Names

DEC-205; CD205 protein

Gene ID

4065(Human); 17076(Mouse)

Uniprot ID

O60449(Human); Q60767(Mouse)

References

1. Naessens, J. et al. (1993) Cross-reactivity of workshop antibodies with cells from domestic and wild ruminants.
2. Gliddon, D.R. et al. (2004) DEC-205 expression on migrating dendritic cells in afferent lymph.
3. Akesson, C.P. et al. (2008) Phenotypic characterisation of intestinal dendritic cells in sheep.
4. Ferret-Bernard, S. et al. (2011) Mesenteric lymph node cells from neonates present a prominent IL-12 response to CpG oligodeoxynucleotide via an IL-15 feedback loop of amplification.
5. Ferret-Bernard, S. et al. (2010) Cellular and molecular mechanisms underlying the strong neonatal IL-12 response of lamb mesenteric lymph node cells to R-848.
6. Fach, S.J. et al. (2007) Neonatal ovine pulmonary dendritic cells support bovine respiratory syncytial virus replication with enhanced interleukin (IL)-4 And IL-10 gene transcripts.

Publications