NeuroMab™ Mouse Anti-PR Monoclonal Antibody (CBP3012)

[CAT#: NAB20102103CR]

Mouse Monoclonal (3D1D12) to PR

Host Species:: Mouse

Species Reactivity:: Human

Applications:: IHC; ELISA

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Product Overview

Description

PGR belongs to the nuclear hormone receptor family and NR3 subfamily. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. The ER and PR status has been used as a predictor of breast carcinoma responsiveness to endocrine therapy and as a prognostic indicator for early recurrence.

Expression Host

Mammalian cells

Immunogen

PR fusion protein Ag22992

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP3012

Applications

IHC; ELISA

Application Notes

IHC : 1:20-1:200

Research Areas

Neural Signal Transduction

Conjugation

Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1905

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Endotoxin Level

Low Endotoxin

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

Official Name

Full Name

Progesterone receptor

Alternative Names

H4 K20 HMTase;
H4 K20 specific histone methyltransferase;
H4-K20-HMTase SETD8;
Histone H4 K20 methyltransferase;
Histone lysine N methyltransferase H4 lysine 20 specific;
Histone-lysine N-methyltransferase SETD8;
Lysine N-methyltransferase 5A;
N-lysine methyltransferase SETD8;
Pr SET 7;
Pr SET7;
PR-Set7;
PR/SET domain containing protein 07;
PR/SET domain containing protein 8;
PR/SET domain-containing protein 07;
PR/SET07;