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Creative Biolabs

Anti-SNAP-25 Monoclonal Antibody (CBP3676)

[CAT#: NAB2012840LS]

Anti-SNAP-25 Monoclonal Antibody [Alexa Fluor 488 ]

Host Species:
Mouse
Species Reactivity:
Human; Rat
Applications:
IHC-P

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Product Overview

Description

Synaptosomal-associated protein 25 (SNAP-25) is a component of the trans-SNARE (t-SNARE) complex. SNAP-25 has been reported to account for the specificity of membrane fusion, and to directly execute fusion by forming a tight complex that brings the synaptic vesicle and plasma membranes together. SNAP-25 has been shown to inhibits both ATP-dependent and independent Ca2+-triggered release of glutamate from central nervous system (CNS) synaptosomal membranes.

Immunogen

Full length, unaltered SNAP-25

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP3676

Applications

IHC-P

Application Notes

IHC-P (0.5- 2 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Alexa Fluor 594; Alexa Fluor 488; Alexa Fluor 498; Alexa Fluor 647; Alexa Fluor 700; APC; APC/Cyanine 7; APC/Fire 750; Biotin; Brilliant Violet 421; Brilliant Violet 510; Brilliant Violet 570; Brilliant Violet 570; Brilliant Violet 605; Brilliant Violet 650; Brilliant Violet 711; Brilliant Violet 750; Brilliant Violet 785; FITC; HRP; PE; Pacific Blue; PE/Cyanine 5; PE/Cyanine 7; PerCP; Spark YG 570
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

SNAP-25

Official Name

SNAP25

Full Name

Synaptosomal-Associated Protein, 25kDa

Alternative Names

TTR

Gene ID

6616(Human); 20614(Mouse); 25012(Rat)
References

1. Snyder DA, et al. 2006. Cell Biochem. Biophys. 45(1):111-23.
2. Nagy G, et al. 2004. Neuron. 41(3):417-29.
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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