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Creative Biolabs
Product

NeuroMab™ Anti-GABA-A-R-Gamma2L/S, Clone N452/30 (CBP8222)

[CAT#: NRP-0422-P121]

Species Reactivity:
Human; Mouse; Rat
Applications:
WB; IHC; ICC

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Product Overview

Immunogen

Fusion protein amino acids 360-445 (cytoplasmic C-terminus) of human GABA-A-R-Gamma2L (also known as Gamma-aminobutyric acid receptor subunit gamma-2 and GABRG2, accession number P18507-2)
Mouse: 100% identity (86/86 amino acids identical)
Rat: 100% identity (86/86 amino acids identical)
>90% identity with GABA-A-R-Gamma2S (amino acids 377-384, LLRMFSFK, unique to Gamma2L)
>50% identity with GABA-A-R-Gamma1 and GABA-A-R-Gamma3

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Isotype

IgG2b

Clone Number

CBP8222

Applications

WB; IHC; ICC

Application Notes

Cross-reacts with GABA-A-R-Gamma2S

Conjugation

Unconjugated
Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.
Target

Target

GABA A Receptor Gamma 2

Official Name

GABRG2

Full Name

GABA(A)R, Gamma2L/S

Alternative Names

GABRG2; CAE2; ECA2; GEFSP3; gamma-aminobutyric acid type A receptor gamma2 subunit; EIEE74; FEB8

Uniprot ID

P18507-2
Product Pictures
IB

Fig. 1 Immunoblot against extracts of COS cells transiently transfected with HA-tagged GABA-A-R-Gamma2L, GABA-AR-Gamma2S or untagged Kv2.1 plasmid probed with N452/30 (left) or rabbit anti-HA (right).

IHC

Fig. 2 Adult rat hippocampus immunohistochemistry.

IB

Fig. 3 Adult rat brain membrane immunoblot.

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