NeuroMab™ Anti-FOS BBB Shuttle Antibody, Clone N486/32
[CAT#: NRZP-0423-ZP74]
- Species Reactivity:
- Human; Rat; Mouse
- Applications:
- WB; IHC; ICC
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-c-Fos BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 1-377 (full-length) of human FOS (also known as Proto-oncogene c-Fos, G0/G1 switch regulatory protein 7 and G0S7, accession number P01100)
Rat: 94% identity (355/377 amino acids identical)
Mouse: 94% identity (353/377 amino acids identical)
<50% identity with FOSL2
Rat: 94% identity (355/377 amino acids identical)
Mouse: 94% identity (353/377 amino acids identical)
<50% identity with FOSL2
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human; Rat; Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
N486/32
Applications
WB; IHC; ICC
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
c-Fos
Official Name
FOS
Full Name
c-Fos
Alternative Names
FOS; AP-1; C-p55; Fos proto-oncogene; AP-1 transcription factor subunit
Uniprot ID
P01100
Publications
Publications (0)
Neural Antibodies
Neural Cell Lines
Kits
For Research Use Only. Not For Clinical Use.
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